STOREY, ANTHONY EAMON,JONES, CLARE LOUISE,BOUVET, DENIS RAYMOND CHRISTOPHE,LASBISTES, NICOLAS,FAIRWAY, STEVEN MICHAEL,WILLIAMS, LORENZO,GIBSON, ALEXANDER MARK,NAIRNE, ROBERT JAMES,KARIMI, FARHAD,LANGS
申请号：
CA2618448
公开号：
CA2618448C
申请日:
2006.08.11
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to a process for preparation of a compound of formula(I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl ； whichcomprises: (i) reaction with fluoride, suitably [18F]fluoride, of acorresponding compound of formula (II): wherein R2 is selected from hydrogen,C1-10alkyl, C1-10haloalkyl, C6-14aryl,C6-14arylalkyl, -(CH2CH2O)q-CH3wherein qis an integer of from 1 to 10； R1 is as defined for the compound of formula(I)； and R3 is a leaving group. Certain novel precursors of formula (II) andradiopharmaceutical kits containing such precursors are also claimed.
