The present invention relates to pyrazolo[3,4-c]pyridine derivatives, the preparation method and medical use thereof. Specifically, the present invention relates to a novel pyrazolo[3,4-c]pyridine derivatives, the preparation method thereof, the pharmaceutical composition containing the same, the use of the same as a therapeutic agent especially as factor Xa inhibitors and the use of the same in the preparation of medicament for the treatment of thromboembolic disorder and the like.本發明涉及吡唑並[3,4-c]吡啶類衍生物、其製備方法及其在醫藥上的應用。具體而言,本發明涉及一種新的吡唑並[3,4-c]吡啶類衍生物、其製備方法及含有該衍生物的醫藥組成物以及其作為治療劑,特別是作為Xa因子抑制劑和在製備治療血栓栓塞等疾病的藥物中的用途。