Opko Ireland Global Holdings, Ltd.;Opko Renal, LLC
发明人:
TABASH, SAMIR P.,BISHOP, CHARLES W.,MELNICK, JOEL Z.,MESSNER, ERIC J.,PETKOVICH, P. MARTIN,WHITE, JAY A.
申请号:
PL11763340
公开号:
PL2552484T3
申请日:
2011.03.29
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxyvitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxyvitamin D.