Opko Ireland Global Holdings, Ltd.;Opko Renal, LLC
发明人:
TABASH Samir P.,BISHOP Charles W.,MELNICK Joel Z.,MESSNER Eric J.,PETKOVICH P. Martin,WHITE Jay A.
申请号：
SI201131862
公开号：
SI2552484T1
申请日:
2011.03.29
申请国别(地区):
SI
年份:
2020
代理人:
摘要：
Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxyvitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxyvitamin D.
