MOORE, Stephen James,NGUYEN, Margaret Thy Luu,HOSTETTER, Daniel R.,VASILJEVA, Olga,FLANDEZ, Jeanne Grace
申请号:
AU2020203910
公开号:
AU2020203910A1
申请日:
2020.06.12
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020203910A120200702.pdf#####Abstract The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one MMP protease, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one MMP protease in a variety of therapeutic, diagnostic and prophylactic indications.