Yuan Liu;Bheemashankar A. Kulkarni;Brian Robert Lahue;Weidong Pan;Matthew Ernst Voss;Stephane L. Bogen;Yaolin Wang;Latha G. Nair;Manami Shizuka;Margarita Kirova-Snover;Craig R. Gibeau;Yao Ma;Yuan Tian
发明人:
Stephane L. Bogen,Yao Ma,Yaolin Wang,Brian Robert Lahue,Latha G. Nair,Manami Shizuka,Matthew Ernst Voss,Margarita Kirova-Snover,Weidong Pan,Yuan Tian,Bheemashankar A. Kulkarni,Craig R. Gibeau,Yuan Liu
申请号：
US13501685
公开号：
US08859776B2
申请日:
2010.10.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides a compound of Formula 1as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
