PROCEDE PERMETTANT D'EFFECTUER LA SYNTHESE D'UN INHIBITEUR DE CETP

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

申请号：

EP06774324.5

公开号：

EP1901741B1

申请日:

2006.06.29

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

An efficient process is disclosed for producing a compound that is an inhibitor of CETP. The last step of the process is the coupling of an oxazolidinone derivative with a biphenyl moiety to provide a compound of formula I. In a specific embodiment of this synthesis, a crystalline product is produced which is characterized as a non-solvated crystalline polymorph.

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