PROBLEM TO BE SOLVED: To provide a bortezomib preparation that has excellent storage stability and can be reconstituted into water in a short time.SOLUTION: The present invention provides a lyophilized preparation containing bortezomib, arginine, and hydroxy dicarboxylic acid and/or a salt thereof, and a method for producing the same.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】保存安定性が優れ、水への再構成時間が短いボルテゾミブの製剤を提供すること。【解決手段】ボルテゾミブ、アルギニン、並びにヒドロキシジカルボン酸及び/又はその塩を含む凍結乾燥製剤、並びにその製造方法。【選択図】なし