PROBLEM TO BE SOLVED: To provide an oral mucosal patch which allows a drug to be efficiently absorbed in the blood and mitigates an uncomfortable feeling such as bitterness and stimulation due to the drug on taking.SOLUTION: The oral mucosal patch 10 has a mucous membrane attaching layer 1 which attaches to the oral mucous membrane and contains a flavoring agent and an edible water soluble polymer, a support layer 2 which is arranged at an outermost layer on the side opposite to the mucous membrane attaching layer 1 and contains an edible water sparingly soluble polymer, at least two drug layers 3 which are arranged in between the mucous membrane attaching layer 1 and the support layer 2 and contain a drug, a flavoring agent, and an edible water soluble polymer, and an intermediate layer 4 which is arranged in between the drug layers 3 and contains an edible water soluble polymer and a flavoring agent.COPYRIGHT: (C)2010,JPO&INPIT【課題】血中へ効率的に薬物を吸収させるとともに、服用時の薬物による苦味や刺激といった不快感が緩和された口腔内粘膜貼付製剤を提供すること。【解決手段】本発明の口腔内粘膜貼付製剤10は、口腔内粘膜に付着し、矯味剤及び可食性水溶性高分子を含有する粘膜付着層1と、粘膜付着層1の反対側の最外層に配置され、可食性水難溶性高分子を含有する支持層2と、粘膜付着層1と支持層2の間に配置され、薬物、矯味剤及び可食性水溶性高分子を含有する少なくとも2つの薬物層3と、薬物層3の間に配置され、可食性水溶性高分子及び矯味剤を含有する中間層4とを備えることを特徴とする。【選択図】図1
