The invention relates to a inhibiting or alleviating agent for amyloid beta (Aβ)-induced damage in hippocampus including an extract from inflamed tissues inoculated with vaccinia virus. The invention also relates to the use of the extract from inflamed tissues inoculated with vaccinia virus in the preparation of an agent for inhibiting or alleviating Aβ-induced damage in hippocampus.本發明係有關針對海馬迴中之β類澱粉蛋白(Aβ)誘發型傷害之抑制或緩解劑,其包含來自經牛痘病毒接種之發炎組織的萃取物。本發明亦係有關來自經牛痘病毒接種之發炎組織的萃取物於製備用於抑制或緩解海馬迴中之Aβ誘發型傷害之用途。