Christopher W. Widenhouse;Gary W. Knight;William B. Weisenburgh, II;John L. Stammen;Charles J. Scheib;Jeffrey L. Aldridge;Mark H. Ransick;Stephanie A. Mutchler;Chunlin Yang
发明人:
Jeffrey L. Aldridge,Chunlin Yang,Charles J. Scheib,Christopher W. Widenhouse,William B. Weisenburgh, II,John L. Stammen,Mark H. Ransick,Stephanie A. Mutchler,Gary W. Knight
申请号：
US13433098
公开号：
US09301753B2
申请日:
2012.03.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A tissue thickness compensator may generally comprise a biocompatible material, a first component, and a second component, wherein the first component and second component form a reaction product to expand the tissue thickness compensator. The first component may comprise a first hydrogel precursor, the second component may comprise a second hydrogel precursor, and the reaction product may comprise a hydrogel. The reaction product may be formed in vivo and/or in situ by contacting the first component and the second component. The first component and/or second component may be encapsulated and configured to release the components when ruptured. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
