Michael J. Cima,Gregory J. Ekchian,Christophoros C. Vassiliou,Vincent H. Liu,Christoph Wald,Sebastian Flacke,Fredric D. Gordon
申请号：
US15190634
公开号：
US10006841B2
申请日:
2016.06.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Trapping devices and methods are provided for capturing a medical analyte, in blood or another biological fluid. The device may include a structural substrate and a binding agent, such as an antibody, affixed to the structural substrate, wherein the binding agent is capable of binding or attaching with a medical analyte, such as a viral particle, and the device is configured for placement in a biological cavity or vessel (containing a biological fluid) in a patient. The trapping device, which may be in a twisted coil shape, is configured to trap at least some of the medical analyte, such a viral particle, present in the biological fluid. The method may include deploying a trapping device into the patients blood vessel after a period following the deployment, removing the trapping device from the biological cavity or blood vessel and then analyzing the trapping device for the presence of the medical analyte.
