< Topic >4 - offer the medicine composition and the gel, and those use methods of containing hidorokishitamokishihuen.SolutionsIt includes with 4 hidorokishitamokishihuen of the 0.105 0.950% and at least C2 C6 alcohol of 1 types of 50 75% and at least the gelatinizer of 1 types of 0.1 5.0% and at least the permeation accelerator of 1 types of 0.1 5.0% and the water medium of the 20 50%, as for percentage (%) the medicine composition which is the weight for the weight of the composition.< Selective figure >It is not【課題】4‐ヒドロキシタモキシフェンを含有する医薬組成物及びゲル、並びにそれらの使用方法を提供すること。【解決手段】0.105-0.950%の4-ヒドロキシタモキシフェンと、50-75%の少なくとも1種類のC2-C6アルコールと、0.1-5.0%の少なくとも1種類のゲル化剤と、0.1-5.0%の少なくとも1種類の浸透促進剤と、20-50%の水性媒体とを含み、パーセンテージ(%)は組成物の重量に対する重量である医薬組成物。【選択図】なし