ЙООН Санг Фил (KR),КО Ки Сеонг (KR),ПАРК Еун Дзеонг (KR),ХОНГ Сунг Дзоон (KR),ПАРК Со Хиун (KR),КИ Мин Хио (KR)
申请号：
RU2015131109
公开号：
RU2015131109A
申请日:
2013.12.27
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Disclosed is a sustained-release lipid pre-concentrate, comprising: a) at least one liquid crystal former b) at least one phospholipid c) at least one liquid crystal hardener and d) at least one bi- or multivalent metal salt, wherein the sustained-release pre-concentrate exists as a lipid liquid phase in the absence of aqueous fluid and forms into a liquid crystal upon exposure to aqueous fluid. The sustained-release lipid pre-concentrate is configured to enhance the sustained release of anionic pharmacologically active substances through ionic interaction between the bi- or multivalent metal salt and the anionic pharmacologically active substances.
