Institut National de la Santé et de la Recherche Médicale (INSERM);Université Nice Sophia Antipolis;Centre National de la Recherche Scientifique (C.N.R.S.)
发明人:
申请号：
EP13792631.7
公开号：
EP2917190B1
申请日:
2013.11.08
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to compound of general formula (1) wherein R1 represents C6-C10 aryl comprising one or two fused rings, wherein from 2 to 5 carbon atoms may be replaced with a heteroatom selected from O, S and NR6, and eventually substituted with from 5 to 11 substituents selected from R6, halo, CN, NO2, CF3, OCF3, COOR6, OCOR6, SO2NR6R7, CONR6R7, NR6R7, NR6COR7, (CH2)p&mdash；NR6R7, (CH2)p&mdash；OR6 and (CH2)pSR6, as well as, if appropriate, their pharmaceutically acceptable salts and/or isomers, tautomers, solvates or isotopic variations thereof. The compounds are useful for the treatment of cancers.
