161066233662676767672P672P62P6The present invention relates to compound of general formula (1) wherein R represents C C aryl comprising one or two fused rings wherein from 2 to 5 carbon atoms may be replaced with a heteroatom selected from O S and NR and eventually substituted with from 5 to 11 substituants selected from R halo CN NO CF OCF COOR OCOR SONRR CONRR NRR NRCOR (CH) NRR (CH) OR and (CH)SR as well as if appropriate their pharmaceutically acceptable salts and/or isomers tautomers solvates or isotopic variations thereof. The compounds are useful for the treatment of cancers.
