A method for increasing fluoride uptake onto a tooth structure of a patient comprises contacting the tooth structure with an oral care composition, which comprises bioactive glass and fluoride. The oral care composition has the following formulation: Ingredient Weight Percent Glycerin 0-90 PEG 0-40 Abrasive 0-30 Thickening Agent 0.1-10 Bioactive glass 0.5-15 Surfactant 0-10 Colorant 0-2.0 Flavor 0.1-2.0 Fluoride 0-5.0 Gum Binder 0-2.0 Sweetener 0-1.0 Colophony Resin 0-75 Ethyl Alcohol 0-25