Istvan Vago,Gyula Beke,Eva Bozo,Sandor Farkas,Katalin Hornok,Gyorgy Keseru,Eva Schmidt,Eva Szentirmay,Monika Vastag
申请号:
US12447157
公开号:
US08481527B2
申请日:
2007.10.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I)whereinR1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.