JAEN, Juan Carlos,JEFFREY, Jenna Leigh,JIN, Lixia,KALISIAK, Jaroslaw,LAWSON, Kenneth V.,LELETI, Manmohan Reddy,KARAKUNNEL, Joyson J.,POWERS, Jay Patrick
申请号：
AU2019231781
公开号：
AU2019231781A1
申请日:
2019.03.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Methods of identifying compounds that modulate the conversion of AMP to adenosine by 5'-nucleotidase, ecto, and that possess particular pharmacokinetic characteristics are described herein. Methods of such compounds, and compositions comprising same, for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, are also provided.
