LARSON, CHRISTOPHER,REID, TONY R.,ORONSKY, BRYAN T.
申请号：
CA3077223
公开号：
CA3077223A1
申请日:
2018.09.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Provided is a fusion protein, e.g., a cytokine receptor fusion protein, e.g., an IL-10 trap, with a novel linker sequence to permit the fusion protein to functionally optimally, e.g., to permit a cytokine receptor portion of a cytokine receptor fusion protein to bind optimally to its target cytokine. The fusion protein, or an expression vector encoding for the fusion proteins, can be used to treat cell proliferative diseases and disorders, including certain forms of cancer and inflammatory disorders.
