COMPOSÉ DE MÉDICAMENT ANTIVIRAL PRÉCURSEUR DE NUCLÉOSIDE CYCLO-PHOSPHATE À BASE DE DISTRIBUTION DU FOIE ET SON UTILISATION

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专利权人:

Zhejiang Paloalto Pharmaceutical Technology Co Ltd

发明人:

XI, Zhijian,XU, Huaqiang,LU, Chunping,WU, Zhongshan,SUN, Feng,ZHANG, Zhenwei

申请号：

EP17814766

公开号：

EP3476854A4

申请日:

2017.06.23

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Disclosed are a liver specific delivery (LSD)-based antiviral prodrug nucleoside cyclophosphate compound and uses thereof, and in particular, provided are a compound of formula (II), and an isomer, a pharmaceutically acceptable salt, a hydrate and a solvate thereof, and the corresponding pharmaceutical composition. The present invention also provides uses of the present compounds, alone or in combination with other antiviral drugs, in the treatment of the diseases caused by hepatitis B virus (HBV), hepatitis D virus (HDV) and human immunodeficiency virus (HIV).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/