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PARTICULATE OLIGOPEPTIDES AS ANTI-ANGIOGENIC DRUGS
专利权人:
NEURONAX;UNIVERSITE DE LIMOGES
发明人:
STEPHANE GOBRON,FABRICE LALLOUE,ROMAIN BIBES,FRANCOIS VINCENT
申请号:
FR1457407
公开号:
FR3024364B1
申请日:
2014.07.31
申请国别(地区):
FR
年份:
2016
代理人:
摘要:
An oligopeptide isolated from an SCO-spondin glycoprotein, characterized by the sequence: —W—S—X1—W—S— X2—C—S— X3—X4—C-G- (SEQ ID NO: 1), in which X1, X2, X3 and X4 represent amino acid sequences that consist of 1 to 5 amino acids. The oligopeptide may be used as a drug for inhibiting angiogenesis, in the treatment of diseases associated with angiogenesis in humans or animals, in particular against tumor angiogenesis. The oligopeptide is suitable in particular for the treatment of brain tumors.
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