Crystals of 1,2-dihydropyridine compounds

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专利权人:

エーザイ・アール・アンド・ディー・マネジメント株式会社

发明人:

有本 達,長戸 哲,菅谷 幸子,浦和 世志雄,伊藤 康一,中 宏行,大前 貴生

申请号：

JP2011224926

公开号：

JP5419944B2

申请日:

2011.10.12

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Disclosed is a method for commercially producing a 1,2-dihydropyrldine-2-one compound represented by the following formula (III) (wherein the ring A and ring B are as defined below and the ring C represents an optionally substituted phenyl group) with high yield and high purity by reacting a compound represented by the following formula (I) (wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and X represents a leaving group) with a boronic acid derivative in the presence of a palladium compound, a copper compound, a phosphorus compound and a base.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/