The present teaching relates to surgical procedure assistance. In one example, a first set of positions of a plurality of sensors are obtained in an image captured prior to a surgical procedure. The plurality of sensors are coupled with a patients body. One or more second sets of positions of the plurality of sensors are obtained based on information from a tracking device associated with the plurality of sensors. The one or more second sets of positions change in accordance with movement of the patients body. One or more similarity measures are calculated between the first set of positions and each of the one or more second sets of positions of the plurality of sensors. A timing at which the surgical procedure initiates is determined based on the one or more similarity measures.