This invention relates to a composition comprising a nanosilicate plate, which is utilized to medicate in an animals gastrointestinal tract to control bacterial infection. The nanosilicate plate composition of this invention can further comprise nano-metal ions such as nano-silver ions and/or antibiotics, capable of being individually medicated to the animal or as a feed additive mixed into animal feed, thereby effectively controlling animals internal bacterial infection without harmful side effect.本發明係關於一種包含奈米矽片之組合物,用於藉由投入腸胃道控制動物細菌感染。本發明之奈米矽片組合物可進一步含有奈米金屬離子(例如奈米銀離子)及/或抗生素,可單獨或做為飼料添加劑混合入飼料投予動物,用以有效控制動物體內之細菌感染,並且對動物不會產生有害的副作用。