An endoscope treatment system includes an operation portion having a distal end and a proximal end, and an endoscope treatment tool having a sheath formed with a lumen that is connected to the distal end of the operation portion and through which a guide wire can be inserted. The guide wire holder in which the tube body in which the guide wire is accommodated is wound in a circumferential shape, and the operation so that the distal end and the base end of the operation portion are located outside the circumference of the guide wire holder. And a fixing member that connects the portion to the guide wire holder.内視鏡用処置システムは、先端、基端を有する操作部、及び前記操作部の前記先端に接続されるとともにガイドワイヤを挿通可能なルーメンが形成されたシースを有する内視鏡用処置具と、前記ガイドワイヤが収容されるチューブ体が円周状に巻かれたガイドワイヤホルダと、前記操作部の前記先端および前記基端が前記ガイドワイヤホルダの円周の外側に位置するように前記操作部を前記ガイドワイヤホルダに連結する固定部材と、を備える。
