PROBLEM TO BE SOLVED: To provide promotion of expression of genes which activate homeostatic functions, by applying heat.SOLUTION: Using an electrical hyperthermic stimulation device, heat stimulus of less than 50°C is applied to at least the heat stimulus originating site which is a site where an extended line of inner periphery between first and second fingers on the sole of left or right foot, and a perpendicular line of inner ankle crosses. Blood volume is increased to promote expression of genes which activate homeostatic functions.COPYRIGHT: (C)2014,JPO&INPIT【課題】熱刺激を与えて恒常性機能を賦活させる遺伝子を発現させる。【解決手段】電気式温熱刺激装置を用いて少なくとも前記熱刺激起源部位の左右の足裏の第1と第2の指間で内側辺縁の延長線上で内踝の垂線と交叉する部位に50℃未満の熱刺激を与えて血液量を増大させて恒常性機能を賦活させる遺伝子を発現する。【選択図】図1