The present disclosure relates to a device, method and system for estimating or monitoring the health condition of a subject. At least one processor, when executing instructions, may perform one or more of the following operations. At least one physiological signal or information including a physiological signal of a subject may be received. At least one physiological parameter of interest may be generated based on the physiological signal. The physiological parameter of interest may be analyzed according to an analysis model. A physiological result may be generated. A recommendation may be provided based on the physiological analysis result.