A process for stereoselective synthesis of lamivudine

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专利权人:

LTD.;SHANGHAI DESANO PHARMACEUTICAL HOLDING CO.

发明人:

LV, FENG,LI, JINLIANG

申请号：

AU2007353748

公开号：

AU2007353748B2

申请日:

2007.06.29

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

A process for stereoselective synthesis of lamivudine, comprising (a) glycosylation of compounds of formula (I) and cytosine or protected cytosine, separating the resulting products by crystallization to afford intermediates of formula (II)； (b) removing the protecting groups of intermediates of formula (II) to obtain lamivudine.

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