JOHNSON, PAUL DAVID,LEACH, ANDREW,LUKE, RICHARD WILLIAM ARTHUR,MATUSIAK, ZBIGNIEW STANLEY,MORRIS, JEFFREY JAMES
申请号:
CA2701057
公开号:
CA2701057C
申请日:
2008.10.09
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention relates to a novel group of compounds of Formula (I) or saltsthereof: wherein Y, Z1, Z2, R1, R4, R5and n are as described in the specification, which may be useful in thetreatment or prevention of a disease or medical conditionmediated through protein kinase B (PKB) such as cancer. The invention alsorelates to pharmaceutical compositions comprisingsaid compounds, methods of treatment of diseases mediated by PKB using saidcompounds and methods for preparing compoundsof Formula (I).