PYRROLO [2,3-D] PYRIMIDINE DERIVATIVES AS PROTEINKINASE B INHIBITORS

• 收藏
• 分享

专利权人:

ASTRAZENECA AB

发明人:

MATUSIAK, ZBIGNIEW, STANLEY,MORRIS, JEFFREY, JAMES,JOHNSON, PAUL, DAVID,LEACH, ANDREW,LUKE, RICHARD, WILLIAM, ARTHUR

申请号：

DK08806741

公开号：

DK2201012T3

申请日:

2008.10.09

申请国别(地区):

DK

年份:

2014

代理人:

摘要：

The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I), methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/