HONG GUAN Ltd.;PEKING UNIVERSITY;BEIJING VITALSTAR BIOTECHNOLOGY CO., LTD.
发明人:
Hongkui DENG,Riguo FANG,Kang LIU,Weifeng YANG
申请号：
US15326216
公开号：
US20170191038A1
申请日:
2015.09.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided is a cocktail of factors for converting/reprogramming non-naïve pluripotent stem cells into TGFβ signaling-independent (TSI) naïve induced pluripotent stem cells (iPSCs). Also provided are methods for reprograming a non-naïve PSC into a TSI naïve iPSC by contacting the cell to be reprogrammed with effective amounts of compounds for a sufficient period of time to reprogram the cell into a TSI naïve iPSC.
