TGFbeta signaling independent naive induced pluripotent stem cells, methods of making and use

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专利权人:

Beijing Vitalstar Biotechnology Co., Ltd.;Peking University;Hong Guan Ltd.

发明人:

Deng, Hongkui,Fang, Riguo,Liu, Kang,Yang, Weifeng

申请号：

AU2015320195

公开号：

AU2015320195A1

申请日:

2015.09.18

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Provided is a cocktail of factors for converting/reprogramming non-naïve pluripotent stem cells into TGFβ signaling-independent (TSI) naïve induced pluripotent stem cells (iPSCs). Also provided are methods for reprograming a non-naïve PSC into a TSI naïve iPSC by contacting the cell to be reprogrammed with effective amounts of compounds for a sufficient period of time to reprogram the cell into a TSI naïve iPSC.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/