A compound of Formula I and/or II and/or a composition comprising a compound of Formula I and/or II is described as well as uses of said compounds and compositions for inhibiting microtubule polymerization, inducing lysosome disruption and/or treating a cancer, including a hematological cancer such as leukemia.Linvention concerne un composé de formule I et/ou II et/ou une composition comprenant un composé de formule I ainsi que des utilisations de ces composés et de ces compositions pour inhiber la polymérisation des microtubules, induire la rupture des lysosomes et/ou traiter un cancer, y compris un cancer hématologique tel que la leucémie.