Scott A. Hilderbrand,Neal K. Devaraj,Ralph Weissleder,Mark R. Karver
申请号:
US14437905
公开号:
US09902705B2
申请日:
2013.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present application relates to functionalized 1,2,4,5-tetrazine compounds. The compounds are useful in compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reactions for the rapid and specific covalent delivery of a “payload” to a ligand bound to a biological target.