A vascular access device comprising: a catheter (212) comprising a primary lumen extending from a proximal end to a distal end of the catheter； and at least one deployable wire (244) secured to the catheter and configured to move relative to the catheter between a delivery configuration and a deployed configuration, wherein the at least one deployable wire (244) in the deployed configuration is configured to engage an inner surface of a wall of a vessel (260) and bias the catheter to engage the inner surface such that a hemostatic connection is formed between the catheter (212) and the inner surface, the hemostatic connection being formed between a portion of an external surface of the catheter surrounding an access opening (218) in a side wall of the catheter and the inner surface of the wall of the vessel.
