介白素－２融合蛋白及其用途农业专利-农业学术服务平台

发明人:: HOSSE, RALF,荷斯　罗夫,荷斯　羅夫,KLEIN, CHRISTIAN,克莱　克里斯汀,克萊　克里斯汀,MOESSNER, EKKEHARD,摩斯那　依哈德,PETERSON, LAURENCE BERNARD,彼得森　劳伦森　柏纳,彼得森　勞倫森　柏納,UMANA, PABLO,优玛那　帕伯罗,優瑪那　帕伯羅,WICKER, LINDA,维克　琳达,維克　琳達,荷斯罗夫,荷斯羅夫,克莱克里斯汀,克萊克里斯汀,摩斯那依哈德,彼得森劳伦森柏纳,彼得森勞倫森柏納,优玛那帕伯罗,優瑪那帕伯羅,维克琳达,維克琳達

摘要：: The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (IL-2). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.概言之，本發明係關於免疫球蛋白與介白素-2(IL-2)之融合蛋白。另外，本發明係關於編碼該等融合蛋白之多核苷酸以及包含該等多核苷酸之載體及宿主細胞。本發明進一步係關於產生本發明之融合蛋白之方法及使用其治療疾病之方法。