In accordance with the present disclosure, there are provided methods for obtaining an active agent useful for the topical treatment of benign epidermal condition(s) in a subject in need thereof. In accordance with certain aspects of the present disclosure, there are provided active agents obtained by the methods described herein. In certain aspects, there are provided formulations for the topical treatment of benign epidermal condition(s) in a subject in need thereof. In certain aspects, there are provided methods for the preparation of formulations for the topical treatment of benign epidermal condition(s) in a subject in need thereof. In certain aspects, there are provided methods for the topical treatment of benign epidermal condition(s) in a subject in need thereof.
