БЛУМЕНФЕЛЬД Марта (FR),КОМПЕР Дельфин (FR),ФРАНКОН Патрисия (FR),ЮТЕН Мишель (FR)
申请号：
RU2014148528
公开号：
RU2014148528A
申请日:
2013.05.07
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A pharmaceutical composition comprising a compound of general formula (I): or a pharmaceutically acceptable salt thereof, characterized in that: - G represents a bond or a linear or branched, saturated or unsaturated hydrocarbon chain containing from 1 to 4 carbon atoms, optionally substituted with one or two alkyl groups, preferably identical, - A represents an aryl group, such as phenyl, optionally substituted: - at the meta or para position: - with a halogen atom or cyanide, alkoxy, haloalkoxy, an acylaminoalkyl or —XR group, where X is —O—, —S—, —SO—, —SO— or —CO— and R is an arylalkyl, cycloalkyl or aryl group, each of which is optionally substituted with one or two substituents, identical or different, such as a halogen atom, an alkoxyl or acyl group, or a cycloalkyl, aryl or arylalkyl group, each of which is optionally substituted with one or two substituents, identical or different, such as an acyl or alkoxy group, and / or in ortho or meta-position and an alkyl group, - B represents an aryl group, preferably phenyl, ortho substituted by a heterocycle, preferably N-cycloalkyl, such as a piperidin-1-yl group, and optionally ortho substituted by an alkyl group, such as methyl, - n is an integer between 1 and 4, preferably between 1 and 2, and more preferably 1, R1 represents an alkoxyl group, such as methoxy, preferably in the ortho position with respect to R3, - R2 represents a hydrogen or halogen atom, such as chlorine or bromine, and and an alkyl group such as methyl is preferred1. Фармацевтическая композиция, включающая соединение общей формулы (I):или его фармацевтически приемлемую соль,отличающаяся тем, что:- Gпредставляет собой связь или линейную или разветвленную, насыщенную или ненасыщенную углеводородную цепь, содержащую от 1 до 4 атомов углерода, необязательно замещенных одной или двумя алкильными группами, предпочтительно идентичными,- A представляет собой арильную группу, такую как фенил, необязательно замещенную:- в мета- или пара-положении:-
