A method for manufacturing a non stick medical tube is provided. The method includes providing a first plastic resin to a tubing extrusion device and providing a second plastic resin to a tubing extrusion device, the second plastic resin comprising a medical grade amide compound. The method further includes mixing the first plastic resin with the second plastic resin and extruding the resin mixture such that the medical grade amide compound is present on an inner surface of the medical tube after extrusion to promote release of contacting surfaces of the inner surface of the medical tubing after contact.