PROBLEM TO BE SOLVED: To provide a methioninase inhibitor containing as an active ingredient a natural plant extract having no influence on the human body, thus usable at ease and having high safety and to provide a composition for an oral cavity and food and drink each containing the methioninase inhibitor.SOLUTION: An extract extracted from a leaf of Morus alba by adding ethanol is used as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】人体に影響がなく安心して使用できる安全性の高い天然植物抽出物を有効成分とするメチオニナーゼ阻害剤及びそれを含有する口腔用組成物並びに飲食品を提供する。【解決手段】クワ(Morus alba)の葉をエタノールを加えて抽出した抽出物を有効成分とする。【選択図】なし