The heart valve assembly has a frame comprising an inflow section, an outflow section, and a connection section located between the inflow section and the outflow section. The inflow section has a plurality of legs extending radially outward and the connection section has greater flexibility than the inner section. The assembly further comprises a plurality of leaflets connected to the connecting section, a valve skirt extending from the leaflet to the inflow section of the frame, and a cuff section, wherein both the leg and the cuff section are provided for engagement with the biological annulus In order to define the cuff.BACKGROUND OF THE INVENTION心臓弁アセンブリは、流入区と、流出区と、流入区と流出区との間に位置する接続区とを備えるフレームを有する。流入区は、半径方向外向きに延びる複数のレッグを有し、接続区は、内部区よりも大きい可撓性を有する。アセンブリは、接続区に連結された複数の小葉と、小葉からフレームの流入区へ延びる弁スカートと、カフ区とをさらに備え、かつ、レッグとカフ区が共に生体の弁輪との係合のためにカフを画定する。【選択図】図1A
