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Aminopyrazine derivative and medicine
专利权人:
Tetsuo Asaki;Katsutoshi Hori;Haruna Naito;Hidetaka Fujihara
发明人:
Hidetaka Fujihara,Tetsuo Asaki,Katsutoshi Hori,Haruna Naito
申请号:
US13147001
公开号:
US08673891B2
申请日:
2010.02.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to a compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound.(I) X is CH or N; R1 is a halogen atom, and R2 is H, a halogen atom, CN, [2], [3], [8], [9], an —O-alkyl, an —O-(saturated ring), etc.[2]: —C(RC)(RD)(RE) (RC to RE each are H, an alkyl, etc.)[3]: —N(RF)(RG) (RF and RG each are H, OH, amino, a (hetero)aryl, etc.)[8]: —C(═O)RL (RL is an alkyl, OH, an alkoxy, amino, etc.)[9]: a (substituted)phenyl;(II) X is >;C—C(—O)RB (RB is a (substituted)amino, an alkoxy, OH, etc.);R1 is a halogen atom; R2 is H; R3 is H or OH; and R3 and R4 each are H or an alkyl.
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