ISHIKAWA, KUMI,KOGA, SHIGERU,KOHNO, YASUSHI,FUJII, KIYOSHI,YOSHIKAWA, KEN
申请号:
EP11850843
公开号:
EP2657241A4
申请日:
2011.12.20
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
[Problem] To provide a diphenyl sulfide derivative which is useful as a pharmaceutical product that has excellent S1P3 antagonist activity. [Solution] The inventors have discovered that a diphenyl sulfide derivative represented by general formula (1) (wherein R1 represents an alkoxy group having 1-6 carbon atoms, R2 represents a propyl group or an allyl group, X represents methylene or an oxygen atom, and Z represents a halogen atom) has excellent S1P3 antagonist activity as a result of extensive researches for the production of a compound that has S1P3 antagonist activity.