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Inhibitors of 11β-hydroxysteroid dehydrogenase type 1
专利权人:
David A. Claremon
发明人:
David A. Claremon,Suresh B. Singh,Colin M. Tice,Yuanjie Ye,Salvacion Cacatian,Wei He,Robert Simpson,Zhenrong Xu,Wei Zhao
申请号:
US12310457
公开号:
US08927715B2
申请日:
2007.08.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention relates to novel compounds of the Formula (I*), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
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