MOSLIN, RYAN M.,WEINSTEIN, DAVID S.,WROBLESKI, STEPHEN T.,TOKARSKI, JOHN S.,KUMAR, AMIT,BATT, DOUGLAS, G.,LIN, SHUQUN,LIU, CHUNJIAN,SPERGEL, STEVEN, H.,ZHANG, YANLEI
申请号:
SG11201503399X
公开号:
SG11201503399XA
申请日:
2013.11.07
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.