SANTELLA, JOSEPH B.,MOSLIN, RYAN M.,WEINSTEIN, DAVID S.,WROBLESKI, STEPHEN T.,TOKARSKI, JOHN S.
申请号:
SG11201503395T
公开号:
SG11201503395TA
申请日:
2013.11.07
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
Compounds having the following formula (I): or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFN alpha by acting on Tyk-2 to cause signal transduction inhibition.