The present invention relates to(R)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one salts, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of sigma receptor and/or μ-opioid receptor associated disease.本發明係關於(R)-9-(2,5-二氟苯乙基)-4-乙基-2-甲基-1-氧雜-4,9-二氮雜螺[5.5]十一烷-3-酮鹽、包含其之醫藥組合物及其在σ(sigma)受體及/或μ-類鴉片受體相關疾病之療法及/或預防中的用途。