您的位置: 首页 > 农业专利 > 详情页

Compositions and methods for ribonuclease-based therapeutics
专利权人:
Ronald T. Raines
发明人:
Ronald T. Raines,Thomas J. Rutkoski,John A. Kink,Laura E. Strong
申请号:
US12247438
公开号:
US08697062B2
申请日:
2008.10.08
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates generally to conjugates of human ribonucleases and water-soluble polymers, compositions comprising the conjugates and methods of using the same. In particular, the present invention provides conjugates of human ribonucleases and one or more water-soluble polymer compositions (e.g., to increase serum half-life and a pharmacokinetic profile, in vivo biological activity, stability, and/or reduce host immune response to the protein in vivo) as well as methods of using the conjugates in the therapy, treatment, and/or prevention of disease (e.g., cancer).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充