Eui Joon JEONG,Mi Jin MOON,Jeong A KIM,Sung Youb JUNG
申请号：
US16471315
公开号：
US20190352335A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a long-acting conjugate for brain targeting comprising a peptide for brain targeting and a physiologically active material, and to a long-acting conjugate comprising a physiologically active material with improved durability and stability, which can pass through the blood-brain barrier (BBB) and comprises a physiologically active material. The long-acting conjugate for brain targeting of the present invention comprising a peptide for brain targeting and a physiologically active material can pass through the blood-brain barrier, thus enabling the treatment of diseases associated with brain diseases, and additionally, can maintain the activity of a physiologically active material in vivo and increase its half-life in the blood.
